![]() ![]() Clinical QKB (Clinical QIAGEN Knowledge Base).COSMIC (Catalogue of Somatic Mutations in Cancer).QIAGEN CLC Genomics Workbench (Desktop).Learn more about its role in oncogenesis and ac. Know your biomarkers: PRKD1 linked to head and neck cancer? – A new cancer gene, PRKD1, has been identified as defining a subset of head and neck cancers.Stop looking for a needle in a haystack – Easily accelerate biomarker and target discovery by exploring and interpreting your data with intuitive, visual biomarker identification too.Single-Cell Genomic Solutions – Explore our powerful solutions for the analysis and interpretation of single-cell gene expression analysis and genomics.Pharmaceutical Development – Whether searching for clinically applicable biomarkers, designing a new companion diagnostic (CDx), or honing your study accrual and go-to-m.Research & Discovery – Powerful digital insights to help you innovate, integrate and translate scientific results into impactful discoveries.Originally published on February 25, 2009. Give it a go and tell us what you think about it. To see more on what Artemis has to offer have a look at the screenshots you will be amazed at what this simple application can do. One fascinating fact that I discovered about Artemis was during the development stages, the authors used it for the annotation of the complete genomes of Camplylobacter jejuni, Neisseria meningitides and the chromosome of Plasmodium falciparum. These can also be modified and moved between files to construct a single annotation table. ![]() The annotation tool allows results from any external analysis programs (EMBL, GENBANK) to be overlaid on the sequence. I do this by having two windows open simultaneously with different zoom levels, making it easier to see where a particular mutation is in respect to the nearby gene and the overall picture. Easily zoom from a single base out to the whole sequence (even if it is a genome – it is a genome viewer after all!).Plot properties of your sequence, such as G+C content, G/C skew, frame shift G+C content, directly against the sequence and its features.Unlike BioEdit, Artemis actually shows the corresponding amino acids when a stretch of bases is selected and vice versa. Use the six frame translation function to quickly pull out open reading frames.So once you get your sequencing data into Artemis, here’s what you can do with it: I was introduced to this application back in university, but have to say, I did not appreciate it until I started working with it. It reads EMBL and GENBANK database entries, or sequences in FASTA or raw format. The Benefits of ArtemisĪrtemis is a Java based application, meaning no installation is required and for once, is an application that runs on all three major platforms Windows, Macintosh and UNIX.Īlso, Artemis can be run as a WWW applet, meaning you can view and annotate sequences even when you are on a public computer. Artemis is a genome viewer, but is extremely handy for viewing and annotating your own sequencing dat (.seq files).Īrtemis was covered briefly by Bala in an earlier article on genome viewers. It’s called Artemis and was developed by the Sanger Institute. But what I have to offer today is a much lighter and equally handy tool. Well now you need some software (preferably free) to analyze your data.īioEdit is a good option. ![]() ![]() Now you’ve got great sequencing results, thanks to Nick’s article on improving sequencing results. ![]()
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